PAI-1 polymorphism in patients with diabetes
نویسندگان
چکیده
منابع مشابه
Association of IFN-¹ Gene Polymorphism with Type 1 Diabetes in Iranian Patients
Background: Type 1 Diabetes (T1D) is a chronic and progressive autoimmune disorder. Cytokines play a critical role in the pathogenesis of T1D. Objective: IFN-¹ polymorphism was investigated in T1D and compared with normal controls. Methods: Thirty patients suffering from T1D and 40 normal controls were studied simultaneously using PCR technique. IFN- ¹ gene was evaluated at position 5’UTR...
متن کاملP-195: The Relationship between PAI-1 Polymorphism with Recurrent Implantation Failure (RIF)
Background: RIF is the most common cause of unsuccessful pregnancy after IVF. Among the various causes of RIF, the role of maternal genetic factors is of great significance. PAI-1 polymorphism is one of the notable polymorphisms in this field. In this study, the relationship between this polymorphism and the recurrent spontaneous abortions and infertility in different populations has been inves...
متن کاملPAI-1 4G/5G polymorphism and plasma levels association in patients with coronary artery disease.
BACKGROUND Type-1 plasminogen activator inhibitor (PAI-1) 4G/5G polymorphism may influence the PAI-1 expression. High plasma levels of PAI-1 are associated with coronary artery disease (CAD). OBJECTIVE This study investigated the influence of PAI-1 4G/5G polymorphism on plasma PAI-1 levels and its association with CAD assessed by coronary angiography. METHODS Blood sample of 35 individuals ...
متن کاملAssociation between PAI-1 polymorphisms and plasma PAI-1 level with sepsis in severely burned patients.
We investigated the association between plasminogen activator inhibitor-1 (PAI-1) polymorphisms and plasma PAI-1 level with sepsis in severely burned patients. A total of 182 patients with burn areas lager than 30% of the body surface area were enrolled in this study. Peripheral blood samples were obtained from 103 patients with sepsis (sepsis group) and 79 patients without sepsis (control grou...
متن کاملStudy of Polymorphism Rs4612666 in NLRP3 Gene in Patients with Type 2 Diabetes in East Azerbaijan
Introduction: Type 2 diabetes is a common multifactorial disease. Studies have shown that the NLRP3 gene plays an important role in insulin resistance. The aim of this study was to investigate the association of rs4612666 polymorphisms of NLRp3 gene with type 2 diabetes in the population of East Azarbaijan province. Methods: In this case-control study, blood samples from 110 patients and 110 h...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine Abstracts
سال: 2016
ISSN: 1479-6848
DOI: 10.1530/endoabs.41.ep454